2025 Volume 32 Article ID: 32_R19
Objectives: To examine the association between high-intensity type ICUs and in-hospital mortality in adult ICUs in Japan. Methods: In this retrospective cohort study, data of adult patients admitted to ICUs between April 2022 and March 2023 was collected from the Japanese Intensive Care Patient Database. We analyzed the association between high-intensity type ICUs and in-hospital mortality using logistic regression adjusted for confounders. Results: The analysis included 65,395 cases admitted to 87 adult ICUs (of which 69 were high-intensity type), with 5,862 in-hospital deaths (9.0%). Regression analysis showed that the adjusted odds ratio for high-intensity type ICUs was 0.96 (95% CI 0.88~1.05, P=0.36). In the subgroup of postoperative patients, the adjusted odds ratio for high-intensity type ICUs was 0.81 (95% CI 0.70~0.95, P=0.008). Conclusion: In Japan, high-intensity type ICUs were not significantly associated with reduced in-hospital mortality. However, a significant association was observed in adult postoperative patients.