PG関連化合物の開発
1989 年 10 巻 6 号 p. 427-436
詳細
1989 年 10 巻 6 号 p. 427-436
Seventh International Conference on prostaglandins and related compounds was held in Florence, May 28-June 1, 1990. Clinical investigation of prostaglandins has been actively performed since the 1st conference held more than 20 years ago. Some of natural prostaglandins and their analogs have been launched in the obstetrical, gastrointestinal and cardiovascular areas. In addition, a thromboxane synthetase inhibitor, ozagrel·Na, has been recently launched for the prevention and treatment of cerebral vasospasms following subarachnoid heamorrhage. Prostaglandins and related compounds including thromboxane and leukotriene synthetase inhibitors and their receptor antagonists will be defined their clinical potential in the near future.
This report reviews clinical studies with those compounds.
