Abstract
LTB4 in the aqueous humor of the 18 eyes with Behçet's disease examined, 10 were active and 8 were stable. The average LTB4 concentrations in the aqueous humor for the active cases were 26.22± 8.96 pmol/ml. The average for the stable cases was 10.87 ± 4.68 pmol/ml. The difference between active and stable averages was statistically significant [P<0.05], and the stable averages were higher than those of controls. These results clearly indicate the significance of LTB4 in ocular inflammation, and patients with Behçet's disease are likely to occur uveitis