抄録
Rheumatoid arthritis (RA) is a chronic inflammatory disease of joint synovium. Several cytokines, including TNF alpha, IL 1, GM-CSF, IL 6, IL 8, MCAF/MCP-1, PDGF, and TGF beta have been detected in joint tissue as well as in synovial fluids from joint of RA. Possible roles of these cytokines in controlling pathophysiological state of RA joints was extensively discussed in this review article.
