Ensho
Online ISSN : 1884-4006
Print ISSN : 0389-4290
ISSN-L : 0389-4290
Neutrophil priming effects on superoxide anion production activity
Akira NishidaToshihiko NakamuraAtsushi Takahashi
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1993 Volume 13 Issue 6 Pages 537-540

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Abstract
Under opsonized zymosan (OZ) stimulation, the cypridinaluciferin analog dependent chemiluminescence (MCLA-CL) of neutrophils (PMNs) shows a different luminescence pattern with and without infection. The noninfected PMN shows the same luminescence pattern as with infection, when primed by tumor necrosis factor (TNF), f-methi-onyl-leucyl-phenylalanine (FMLP) and phorbol myristate acetate (PMA) . From these findings, it is considered that the PMNs when infected, is primed by an increasing number of various mediators.
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© The Japanese Society of Inflammation and Regeneration
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