顎嚢胞の発症因子と抑制機序に関する臨床生化学的研究 (II)

―特に, 嚢胞腔洗浄による嚢胞増大の抑制効果―

抄録

When a cyst is infected, the cyst wall is damaged. The treatment procedure using the irrigation method is as follows : before the operation, the cyst fluids in cyst cavities are replaced with a solution of Solcoseryl^® or 20% glucose, containing antibiotics ; the infection of the cyst cavity disappears and osmotic pressure decreases, so the formation of free radicals ( O^-/⋅₂, HO⋅) and lipoperoxides (TBARs, PC-OOH) in the cyst wall is suppressed, as is the function of 12-HETE, LTB₄ and 6-keto-PGF₁α generated in the cyst walls. The blood circulation in the capillary vessels of the connective tissues in the cyst walls improves, and the cyst gradually diminishes in size until bone remodelling takes place. Recovery occurs soon after the operation.