Abstract
In this study, we measured nitric oxide (NO) concentration in exhaled air before and after attacks in asthmatics, and during exercise in healthy and asthmatic subjects.
The results revealed that NO concentration significantly increased after asthmatic attacks as compared with that before attacks, and that NO showed a tendency to decrease during exercise in healthy subjects whereas it increased in asthmatics. The decrease in healthy subjects depended on increased minute ventilation and the increase in asthmatics seemed to be based on induction of chemical mediators by exercise.
We conclude that NO concentration in exhaled air changes according to asthmatic states.
