Abstract
CCA {disodium 4-chloro-2, 2'-imminodibenzoate} is a new compound synthesized and developed by Chugai Pharmaceutical Co., Ltd. CCA has been suggested to have an immuno modulating effect in animals. In this paper, we presented the effect of CCA on the PFC and RFC (rosette forming cell) response for SRBC in vivo. We have already reported that the immunoresponse in C3H/He mice decreased with the age. In this experiment, we used aged C3H/He mice and found that the number of PFC and RFC in the aged C3H/He mice was increased by the treatment of CCA. This results suggest that the decreased immunoresponse in the mice was recovered to normal level by CCA treatment.
