抄録
Recent development of biotechnology has brought extensive advance in medical care and supplies. Especially, the tissue engineering is one of the most attractive approaches to regenerate the damaged organs. For example, it is now possible to reconstruct the bone tissue by culturing bone marrow derived mesenchymal stem cells. Tissue Engineering Research Center (TERC) at the National Institute of Advanced Industrial Science and Technology (AIST) was established in April, 2001. The TERC has clean rooms (class 10, 000 and 1, 000) handling only human cells for clinical applications. We report herein about culture technique and safety of the tissue engineering products in repect of clinical application in Orthopedic fields.