Reproductive Immunology and Biology
Online ISSN : 1881-7211
Print ISSN : 1881-607X
ISSN-L : 1881-607X
Effects of Environmental Chemicals on Cell Division and Chromosomal Positioning
Kosuke OikawaYoichi MatsudaMasahiko Kuroda
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JOURNAL FREE ACCESS

2009 Volume 24 Issue 2 Pages 70-76

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Abstract
Environmental chemicals such as dioxin are known to have toxicities causing tumor promotion and serious reproductive and developmental defects. In this review, we focus on cell division, and discuss the effects of dioxin and related chemicals on the molecules involved in mitosis and/or meiosis. Dioxin affects various steps of biological processes including mitosis, meiosis, arrangement of chromosomal positioning and epigenetic regulation. Although the molecular mechanisms of these effects are still unclear, we provide recent findings of novel effects of dioxin and related compounds on them.
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© 2009 Japan Society for Immunology of Reproduction
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