日本リウマチ・関節外科学会雑誌
Online ISSN : 1884-9059
Print ISSN : 0287-3214
ISSN-L : 0287-3214
右大腿部悪性軟部腫瘍を疑った色素性絨毛結節性滑膜炎の1例
二見 俊郎大野 司山徳 義郎山本 真
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ジャーナル フリー

1985 年 4 巻 2 号 p. 117-121

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The patient, 36-year-old male, first came to our clinic with the complaints of a subcutaneously located huge tumor-like formation of the anterior aspect of his left femur around the knee joint and slight limitation of the affected knee joint motion.
Plain X-ray showed no marked abnormality, but angiography demonstrated a significant hypervascularity at the affected area, CT scan showed the invasion of a tumor-like tissue into the quadriceps muscle.
With such results, the possibility of a malignant soft-tissue tumor could not be excluded.
In the subsequent operation, a huge tumor 15cm by 13cm in diameter, and weightjngd 230g was excised. The tumor had a connection to the joint cavity and had also entered the muscle.
Histological examination showed lamitation of synovial-like cells, hemosiderin deposits and sparse foamy cells, which are the characteristic features of pigmented villonodular synovitis. The most striking pathological findings were the direct invasion of the muscle fiber.
Radiation therapy with a total of 2800rads was initiated post-operatively. Now, 7 months after the operation, the patient is well and without local recurrence, but the significant limitation of joint motion has remained.
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