Identification of key bacterial taxa and metabolic pathways affecting gut organic acid profiles in early life

Abstract

Infant gut microbiota development affects the host physiology throughout life, and organic acids are important key metabolites mediating microbiota-host relationships. This review summarizes our recent study on early-life gut microbiota development and its association with gut organic acid profiles. We further discuss key bacterial taxa, metabolic pathways, environmental factor, and bacterial cross-feeding that affect gut organic acid production in early life.