Spindle-cell variant of diffuse large B-cell lymphoma in the uterine cervix: a case report and literature review

Abstract

We report a case of spindle-cell variant of diffuse large B-cell lymphoma (Sp-DLBCL) occurring in the uterine cervix of a 50-year-old female patient. A review of the literature revealed that most reported cases of Sp-DLBCL arise in the skin, with only seven previously documented cases occurring in the uterine cervix. This report highlights the importance of considering Sp-DLBCL in the differential diagnoses of spindle-cell tumors of the uterine cervix, although lymphoid neoplasia is relatively rare in this organ. We also emphasize the importance of deep tissue biopsy to minimize artifacts caused by tissue damage and careful interpretation of immunostaining results.