日本網内系学会会誌
Online ISSN : 1883-6801
Print ISSN : 0386-9725
ISSN-L : 0386-9725
CD4-, CD8+を示した成人T細胞白血病・リンパ腫の2例
佐分利 能生菊池 博樋園 和仁大塚 英一小野 敬司堀 高志那須 勝糸賀 敬井上 聡一横山 繁生中山 巌田北 祥子河野 宏三舟 求真人宮本 勉
著者情報
ジャーナル フリー

1991 年 31 巻 1 号 p. 65-71

詳細
抄録
Two cases of adult T cell leukemia/lymphoma (ATLL) with unusual surface markers such as CD4- and CD8+ have been reported.
Case 1: A 77-year-old male was admitted to our hospital with complaints of abdominal pain and swelling of testis and lymph nodes. Case 2: A 65-year-old male noticed a lymph node swelling in his right submandibular region. Lymph nodes taken from both patients were diagnosed as non-Hodgkin's lymphoma under histological examination. Integration of HTLV-I proviral DNA in the lymphoma cells and positive HTLV-I antibody in the serum disclosed that these cases were indeed ATLL although tumor cells expressed an unusual combination of the surface markers i.e. CD4- and CD8+. There have been reports as to heterogeneity of the surface markers in ATLL. We believe that these cases could be a rare variant of ATLL.
著者関連情報
© 日本リンパ網内系学会
前の記事 次の記事
feedback
Top