Abstract
Our major goal is to develop advanced analytical techniques for biomedical researches based on the Raman spectroscopic applications of an electronically tuned Ti:sapphire laser and the developments of advanced spectroscopic tools. Three studies are on going in our laboratory: 1) extraction of Raman signals from fluorescent interference, 2) extraction of Raman signals of no-resonant species in the presence of resonant species, 3) development of fiber-optic Raman probes less than 750 μm in diameter. Three new spectroscopic techniques and the development of a micro Raman probe 600 μm in diameter are reviewed in the present paper.