Evaluations of PDT and PDD used for Skin Cancers in Department of Dermatology, Yamaguchi University

Abstract

Photodynamic therapy (PDT) and photodynamic diagnosis (PDD) have been reported to be useful for the treatment of the skin cancers and deciding the lesion. We performed PDT for the treatment of Bowen′s disease and cutaneous T-cell lymphoma, and PDD for deciding the lesion of extramammary Paget′s disease, using 20% 5-aminolevulinic acid (ALA) in the past 5 years. We had a relapse in each case performing PDT for the treatment of Bowen′s disease and cutaneous T-cell lymphoma, whereas PDD was useful deciding the accurate lesion of extramammary Paget′s disease and detecting remaining Paget′s cells. We have to recognize limitations of PDT and PDD, and make a deliberate case selection.