Abstract
Photodynamic diagnosis (PDD) has been applied for the detection of flat lesion of bladder cancer, in particular carcinoma in situ. Recent meta-analysis has revealed PDD has an evidence of improving patient outcome in terms of tumor recurrence as well as finding optically non-visible tumor lesions. This effect may contribute to standardization of the TURBT treatment among institutions. Oral administration of 5-ALA may confer the PDD on the new detection method for other urological malignancies, such as the detection of surgical margin during partial nephrectomy, or radical prostatectomy. Herein, upfront publications concerning PDD on urological malignancies are reviewed in this article.