Photoacoustic Imaging as a Novel Modality for Detection and Management of Localized Prostate Cancer

Abstract

Photoacoustic imaging is a novel non-invasive modality enabling detection of hemoglobin and facilitating acquisition of microvessel distribution in the same manner as ultrasonography without using contrast agents. In resected radical prostatectomy specimens, strong signals were detected on the postero-lateral surface of the prostate, where network of neurovascular bundle was abundant. Our results raise a possibility that photoacoustic imaging could be a novel modality for detection and management of localized prostate cancer.