Indications and Practice of Photoimmunotherapy

Abstract

Photoimmunotherapy is a novel treatment approach combining the administration of a cancer-specific antibody–photosensitizer conjugate with laser light illumination. Pioneering globally, it has been approved for insurance coverage for head and neck cancer in Japan and is available for clinical use. Owing to its novelty, determining its applicability can often be challenging. It is crucial to make decisions regarding its suitability by considering the patient’s risks and benefits as well as insurance coverage, contraindications, treatment methods, and potential adverse events.