The Journal of Japan Society for Laser Surgery and Medicine
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
The Prediction of Acute Rejection in Renal Transplantation by Laser Light Scattering Device.
Seimei TANIMURAYoshio TAGUCHITakao KUNORITakashi SASAKIKazuaki MIURAIwao KANEDASusumu SATOMIMorio KASAIAkio YAMAGISHIChoichi TAKYUShoji IZAWAHumio INABA
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1980 Volume 1 Issue 1 Pages 105-112

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Abstract

An automated biological cell sorting system (ABCS) based on laser light scattering method have been designed and constructed for clinical applications. Using the ABCS, the sizes of various lands of cells were measured and cells were separated on their sizes. Daily morphological changes in lymphocytes after stimulation of mitogen or mixed lymphocyte culture were cautiously examined.
In 10 cases of renal patients, the daily morphological changes in lymphocytes before and after renal transplantations have been measured, Marked changes of size of lymphocytes were observed during acute rejection crisis, especially the changes were observed just before rejection episodes. Thus, acute rejection crisis could be predicted rapidly and easily by the ABCS.

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