Laser Absorption Spectroscopy for Blood Glucose Measurement

Abstract

We have developed a laser absorption spectroscopy for blood glucose measurement based on the use of carbonic gas laser which permits the glucose density of human tissues to be measured continuously without taking blood samples.
As compared with conventional types of infrared spectroscopes, the newly developed laser absorption spectroscope features a higher light sources brightness and combined use of laser beam displaying excellent wavelength resolution and attenuated total reflection (ATR) plate. The ATR plate is an attenuated total reflection prism with high refraction index containing arsonium selenide.
Regarding its principle of measurement, the ATR plate is press against the patients lips or other viscous membrane tissue and the carbonic gas laser beam made, to penetrate to a depth of about 30 microns in the tissue for multiplexed. reflection. The absorbed spectrum is measured and fed into a minicomputer for direct readout of glucose density.
Conventional methods for measuring the kinds or densities of molecules in human tissues optically require the use of visible light rays. However, the newly developed laser absorption spectroscope employs the ATR prism, by which it is possible to use a carbonic gas laser lying in the range of infrared rays for measuring the absorbed spectrum.
Since this new spectroscope permits the glucose density in the blood to measured in real time and very accurately without extraction of blood serum from the body as with conventional great value in this field.