The Journal of Japan Society for Laser Surgery and Medicine
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
Biphoton Emission and Laser Irradiation in the Process of Wound Healing
H. ItoY. KurokawaM. UsaY. taguchiH. Inaba
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1990 Volume 11 Issue Supplement Pages 77-80

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Abstract
Spontaneously ultraweak light (biophoton) from wound surface of mouse was detected by two-dimensional photon counting system. Biophoton emission from the wound changed with the post operative time. The initial emission during the first day was not specific to the wound, but a clear wound shape discerned about two days later. The most intensive emission part of the wound moved from the edge to the center in the process of wound healing. We proposed that biophoton emission and its changes are related the external stimulus (wounding) and containd important biochemical and medical imformation.
In order to examine the optimal condition of irradiation of 810nm AlGaAs diode laser for the acceleration wound healing, the experimental wound was irradiated on five conditions. The experimental animals (Wister strain male rat) were divided into fivr groups noticing the energy density and the power density of 810nm laser. One of two circular wounds with 1.0cm diameter on the rat dorsal was irradiated. The condition of irradiation was as follows; A 1J/cm2-17mW/cm2 B 1J/cm2-50mW/cm2 C 10J/cm2-17mW/cm D 10J/cm2-50mW/cm2 E 50J/cm2-200mW/cm2. As a result, the most effective condition of irradiation on accelerating of wound healing was C group. Both irradiated side and non irradiated side irradiated with the condition C was healed faster than the other 4 groups and control. It is necessary for the resolution of the mechanism of the biostimulation effect to examine the optimal condition of irradiation (wavelength, mode, energy density, power polalizing characteristics, etc.) and the transmittance charcteristics of the irradiating object.
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