Abstract
A newly developed fiber-optic pulsed photo-thermal radiometry (PPTR) equipment and its application for gastric diagnosis were described. The PPTR is one of radiometry analysis which was developed by Tam in 1970s. Optical absorption and thermal diffusion characteristics of samples can be simultaneously obtained by this method. Therefore, this PPTR method can offer different information which is obtained by fluorescence spectrometry, refractive spectrometry and ultrasonic imaging, which have been utilized with endoscope.
We had developed fiber-optic PPTR equipment and we had applied it to urological and cardiovascular samples, We successfully improved this equipment using newly designed fiber-tip and lock-in amplifier. Since the detectivity and sensitivity of the equipment were remarkably improved, a thin (490μm) and long (2m) infrared fiber which is formed detection line could be employed.
Intra-gastric measurement is one of the best application of the fiber-optic PPTR method, since the air atmosphere which is necessary to attain this method was easily obtainable. In situ measurement of rabbit gastric wall suggested that fiber-optic PPTR may be applied to diagnose ulcer advance and/or prevent wall perforation by therapeutic laser ablation.
