Abstract
Background and Objective: This study evaluated the use of low-output, non-contact irradiation by KTP laser (potassium-titanyl phosphate) (λ=532nm) for hemangiomas using a rabbit liver model, and calculated the tissue temperature distribution using the thermal conduction equation.
Study Design/Materials and Methods: Laser irradiation was applied to the liver of rabbits at various power densities(1.0 to 8.0 J/cm2). Paraffin sections of irradiated sections were prepared, and histology was correlated with the tissue temperature distribution calculated from the thermal conduction equation.
Results: When the measured depth of coagulation was introduced into the thermal conduction equation, laser irradiation of about 4.0 J/cm2was required to raise the tissue temperature to 60°C at a depth of 1mm with an irradiation distance of 2.5mm.
Conclusion: Coagulation therapy by non-contact irradiation with a KTP laser is appropriate for treating hemangiomas. However, as the depth of coagulation is limited to the surface of the irradiated site, multiple sessions may be required for complete eradication of the lesion.
