Abstract
Contact irradiation of Nd-YAG laser was applied to bovine liver, mouse transplantable colon 38, and human gastric adenoma by a newly developed artificial sapphire probe, which is superior to quartz fiber is its heat resistance, hardness, and mechanical strength. The laser being applied to bovine liver at variable energy and irradiation time, the relationship between energy and effectiveness was consequently found out to be determined more aculately in contact method. The differences in tissue coagulation between CO2 and distilled water used to protect the probe were also studied and concluded that adhesion of coagulated tissue could be prevented by allowing an outflow of distilled water and the abdominal distention relieved in the clinical treatment.