Abstract
Pulse CO2 laser was used to investigate the cutting mechanism of biotissue by KrF excimer laser. At macroscopic view, pulse CO2 laser with low repetition rate was experimentally clarified to have same cutting ability to tissue without carbonization as KrF excimer laser. The high peak power laser with short pulse duration is supposed to have a great influence on the unnatural tissue layer near the irradiation surface and its cutting mechanism. The laser absorption by water involving in tissue will be important factor in analyzing the laser cutting mechanism.