Measurement of Cell Electrophoretic Mobility Variation Caused by Low-Energy Laser Light Irradiation

II. Experiment using synchronized HeLa Cancer Cell

Abstract

Variation of cell electrophoretic mobility (E.P.M.) of synchronized HeLa cancer cells caused by low-energy Ar laser irradiation with the energy density of 10mJ/cm2 were measured for the first. This low-energy laser irradiation on HeLa cells was performed at three phases of the cell cycle, namely G₁, S and G₂-M. Some differences between laser light irradiated cells and non-irradiated (control) cells were observed for the cases of cultured HeLa cells with G₁ and G₂-M phase irradiation in contrast to the S phase irradiated cells. These results appear to suggest the correlation between the effect of low-energy laser irradiation and the cell cycle.