The Journal of Japan Society for Laser Surgery and Medicine
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
Photodynamic Therapy with Lipiodol -Pheophorbide a Sensitization for Experimental Liver Cancer
Y. Nishiwaki, S. Nakamura, S. Suzuki, S. Sakaguchi, M. Nakazato, M. Konno, Y. Yamashita, K. Ohta
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1987 Volume 8 Issue 3 Pages 53-54

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Abstract

To treat Liver cancer with PDT, it is essential to accumulate much more photosensitizer in the to than in normal Liver tissue. We succeeded in accumulating a sensitizer selectively in liver tumor by intraarterial administration of pheophorbide a dissolved in Lipiodol. With this technique and activation by 670 nm Light of Nd-YAG dye laser, we produced severe PDT necrosis in Liver tumor of the rat without damage of surrounding Liver tissue.

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