2010 Volume 70 Issue 4 Pages 326-332
We researched the detection of bacillus of the Candida genus and the change of β-D glucan value in 34 patients with β-D glucan values of more than 11 pg/ml on post operative day (POD) 1, among 149 patients who had surgery from October to April in 2003. A culture test was used (a pharynx/expectoration, gastric juice, urine, feces, drain, others) and a β-D glucan value. We administered an antifungal drug to patients with a β-D glucan value of more than 11 pg/ml on POD 1. Postoperative mycotic detections were differentiated to mycotic detections of the hospital, which comparatively tended to show much fewer Candida albicans than Non-albicans. Transitions of the β-D glucan value of all patients showed that the β-D glucan value was high on POD 1 (17.1 ± 2.6 pg/ml), decreased after POD 3, and changed to a negative value (3.5 ± 1.3 pg/ml) for all cases until POD 7. In liver cancer and colon cancer, the β-D glucan value of POD 3 tends to become higher than that of POD 1. It seems that aggravation may be prevented by early administration of an antifungal agent for cases in which the postoperative β-D glucan value is positive and fungi are detected after surgery.
