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Volume 70 (2010)
- Issue 6 Pages 445-
- Issue 5 Pages 377-
- Issue 4 Pages 281-
- Issue 3 Pages 203-
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Volume 70, Issue 4
Displaying 1-8 of 8 articles from this issue
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Final Lecture
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[in Japanese]2010 Volume 70 Issue 4 Pages 281-287
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSDownload PDF (527K)
Review
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2010 Volume 70 Issue 4 Pages 288-292
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESS
Original
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Ayako AKIZUKI, Noriyoshi SUMIYA, Yasuhiro HOTTA, Takashi MIYAZAKI2010 Volume 70 Issue 4 Pages 293-301
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSThe prolabium of the bilateral cleft lip and palate is deformed and has insufficient tissues. It is necessary to use the lateral labia to reposition the alveolar form. For this purpose, we performed a two-stage procedure. First, one side is closed completely using the maximum amount of tissue available. Concomitantly, incomplete closure is performed on the other side. The result at the end of the first stage of the procedure approximates unilateral incomplete closure. Secondary lip repair procedures are performed six months later. Complete closure is performed on the incomplete closure side. At the same time, the hard palate is closed with the vomer flap. Using this palatal model, the morphological change as a result of the primary repair of the bilateral cleft lip and palate approximates normal morphology of the palate.View full abstractDownload PDF (846K) -
—with Special Focus on Surgery and Hormone Therapy Experience—Yohei OHTAKA, Mizue SHIROMARU, Takehiko ITO2010 Volume 70 Issue 4 Pages 302-314
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSHormone therapy is commonly used for breast cancer patients in Japan. Although horomonotherapy is recognized to have few side effects, complications such as hot flashes may cause impaired quality of life of the patients. The aim of the present study was to reveal the psychological state of breast cancer patients through an exploratory analysis of their narratives by Text Mining Studio, a text mining software. Participants were ten breast cancer patients who had experienced both surgery and hormone therapy. The narratives were collected in a semi-structured interview and analyzed by using the software. Word frequency analysis showed that the words used in narratives were associated with not only therapy but also patients' daily life, such as family and work. The words were classified into three areas: therapeutic experience, daily life experience, and psychological and physical conditions. In the hormonotherapy category, words related to psychological states were rarer than in the operation category. Correspondence analysis showed two clusters of participant: those with sufficient family support narratives and those with narratives of suffering from symptoms. Analysis of patients' narratives revealed that mitigation of physical symptoms led to alleviation of anxiety in relation to surgery. In relation to hormone therapy, there was no such relationship between physical and psychological distress. Narratives of younger patients are needed in a future study. The present study abductively suggests that a variety of support for breast cancer patients by nursing professionals is necessary to alleviate physical pain and psychological anxiety. In addition, the strong support from family members helps patients confront their lives positively. Construction of support contents on the basis of understanding variations of patients' narratives is an important task for professionals.View full abstractDownload PDF (429K) -
Shuji OISHI, Mayumi TSUJI, Hitomi HASEGAWA, Makiko TAJIKA, Yuko IRIE, ...2010 Volume 70 Issue 4 Pages 315-325
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSRecently, oxidative stress caused by direct contact of blood with dialyzer membrane surfaces in hemodialysis patients has been reported. It is well known that oxidative stress serves as an important risk factor for the development and progression of several complications in hemodialysis patients. In particular, patients with diabetes mellitus are associated with increased oxidative stress. High blood glucose may generate free radicals to induce apoptosis in cells. The purpose of this study was to elucidate the mechanisms of cell apoptosis induced by high glucose and hydrogen peroxide (H2O2). To induce oxidative stress, human monocytic (U937) cells were exposed to high glucose for 2 or 6 days; H2O2 was added to the cells on the last day. Exposure of U937 cells to H2O2 resulted in a significant increase in cellular apoptosis and the generation of ROS, and a decrease in mitochondorial membrane potential. Under high glucose conditions, treatment with H2O2 significantly promoted these actions; however, pretreatment with antioxigen agent N-acethyl-cysteine (NAC) in H2O2-induced apoptotic cells significantly suppressed the induction of apoptosis and oxidative stress. After incubation with H2O2 or high glucose and H2O2, caspase-3 activity also significantly increased in U937 cells; however, pretreatment with NAC significantly reduced the increases, as compared with H2O2 or high glucose and H2O2. Treatment with high glucose and H2O2 did not promote caspase-3 activity, compared with treatment with H2O2 alone. In conclusion, these results showing that high glucose promoted and amplified apoptosis by oxidative stress in this model demonstrated that patients with diabetes mellitus undergoing hemodialysis treatment accelerate apoptosis induction. Oxidative stress by high glucose may induce the caspase-independent apoptotic pathway.View full abstractDownload PDF (672K) -
Takahiro UMEMOTO, Kazuyoshi ISHIBASHI, Mitsuo SAITOU, Gaku KIKAWA, Hir ...2010 Volume 70 Issue 4 Pages 326-332
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSWe researched the detection of bacillus of the Candida genus and the change of β-D glucan value in 34 patients with β-D glucan values of more than 11 pg/ml on post operative day (POD) 1, among 149 patients who had surgery from October to April in 2003. A culture test was used (a pharynx/expectoration, gastric juice, urine, feces, drain, others) and a β-D glucan value. We administered an antifungal drug to patients with a β-D glucan value of more than 11 pg/ml on POD 1. Postoperative mycotic detections were differentiated to mycotic detections of the hospital, which comparatively tended to show much fewer Candida albicans than Non-albicans. Transitions of the β-D glucan value of all patients showed that the β-D glucan value was high on POD 1 (17.1 ± 2.6 pg/ml), decreased after POD 3, and changed to a negative value (3.5 ± 1.3 pg/ml) for all cases until POD 7. In liver cancer and colon cancer, the β-D glucan value of POD 3 tends to become higher than that of POD 1. It seems that aggravation may be prevented by early administration of an antifungal agent for cases in which the postoperative β-D glucan value is positive and fungi are detected after surgery.View full abstractDownload PDF (488K)
Case Report
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Atsushi SHIRAHATA, Yoshikuni HARADA, Kazuhiro KIJIMA, Makiko SAKATA, K ...2010 Volume 70 Issue 4 Pages 333-337
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSA 56-year-old man visited our hospital because of a mass in the middle left abdomen. An abdominal computed tomography scan showed an enhanced diffuse thickening of the small intestinal wall. However, it was difficult of make a preoperative diagnosis because endoscopic biopsy was impossible. Therefore, single-incision laparoscopic surgery (TANKO) was performed in order to diagnose and treat the smallintestinal tumor. The laparoscope revealed a small area intestinal cancer that had serosal invasion, peritoneal dissemination and lymph node metastasis. Resection of the small bowel and anastomosis were done under umbilical minimal incision. We were able to perform a less invasive surgery and effective diagnosis and resection with TANKO and report this case of small bowel cancer for which TANKO was very useful.View full abstractDownload PDF (496K) -
Rui INAMURA, Yuko HASEGAWA, Satomi AZUMA, Leon KOBAYASHI, Takasi TOI, ...2010 Volume 70 Issue 4 Pages 338-342
Published: August 28, 2010
Released on J-STAGE: May 27, 2011
JOURNAL FREE ACCESSWe report a case of survival from cardiac arrest caused by acute PTE under spinal anesthesia. A 58-year-old man had open-reduction surgery for a patella fracture. We performed spinal anesthesia, and then the patient suffered from cardiac arrest just after tourniquet inflation. With appropriate CPR, the palmus restarted 8 minutes later. There were no right heart overload findings. An echocardiogram did not show any thrombus in the right atrium. An ultrasound study focusing on the inferior limb demonstrated a thrombus in the diseased limb side femoral vein. Subsequently, we started treatment for pulmonary thromboembolism. Venography revealed the thrombus in the lower extremity. A filter for the thrombus was placed in the IVC. It is essential that the anesthesiologist be aware of the possibility of pulmonary thromboembolism in the case of acute circulatory collapse and to treat the patient as soon as possible. Therefore, it is necessary that anesthesitlogists have appropriate diagnostic skills and therapeutic knowledge for this entity.View full abstractDownload PDF (496K)
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