Abstract
Numerous reports have been published related to the fact that, the excretion of pyrvric, lactic and α-keto-glutaric acid etc. in the urine is increased following the fructose injection to a man when compared with the results with glucose injection. Derived from the above facts, the difference between fructose and glucose in their metabolic pethways in the organismus was presumed. Therefore, the authors planned this experiment from the view point that a similar difference might exist concerning citric acid, which is the intermediates of the “Krebs's cycle ”. The following is the results obtained.
1) No definite tendency in the fluctuation of the amount of citric acid in, the urine was recognized when intravenous injections of fructose and glucose was given.
2) The excretion of calcium in the urine was found increased at 15 minutes after the injection of 50% glucose and 20% fructose when compared with the controls and with the result of 20 % glucose. However, no statistically significant change in urine citric acid was occured at any time after the both sugar injection, although a positive correlation was recognized between the amount of citric acid and the calcium in the urine.
3) A positive correlation between the pH of the urine and the amount of citric acid excreted in the urine was recognized.
4) The citric acid content in the urine and the citric acid concentration in the serum are not necessarily in parallel, but a positive correlation was recongized between them.
