Abstract
In the present paper, the authors investigated the fluctuation in the circulating eosinophil level during sleep induced by the injection of barbital, and the eosinopenia for ACTH action in this case. The following results were thus obtained.
1. The eosinophil level was found elevated during sleep induced by the injection of barbital, and it was lowered with the waking.
2. The eosinopenia reaction induced by ACTH during sleep was found stronger than the normal.
In view of the above, the authors considered that sleep itself elevates the eosinophil level, and that the irritability of the pituitary adrenocortical system during sleep is rather enhanced, consequently, the alarm reaction appears more markedly.