Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
STUDIES ON THE PHAGOCYTIC ACTION OF NEUTROPHILIC LEUCOCYTES AND PITUITARY-ADRENOCORTICAL FUNCTION
Report 3. Effect of dietary components on phagocytic action of neutrophilic leucocytes
Iwao Honda
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1958 Volume 18 Issue 6 Pages 507-513

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Abstract
The phagocytic action of neutrophilic leucocytes and hematologic changes were studied in Wistar male rats following the feeding of diets containing protein, fat and carbohydrate. The following results were obtained.
1. The dietary components have no effect on the degree of the phagocytic action.
2. No remarkable effect observed in phagocytosis in fat feeding rats, however, a slight a increase phagocytic actionwas observed following 6 days' feeding of protein or carbohydrate.
3. Slight neutrophilia observed by the feeding of protein or carbohydrate for two days and it recovered to the control level after 10 days.
4. The increase of phagocytosis appeared following appearance of neutrophilia.
From the investigations described above, it is suggested that protein or carbohyarate feeding will induce an alarm reaction but not in case of fat. Therefore, it is. demonstrated that the dietary components have an influence on leucocytic phagocytosis through pituitary adrenal axis.
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