Abstract
Cholinesterase (ChE) in human placenta, maternal and fetal blood in physiological and morbid conditions, were studied manometrically, using Acetyl-β-methylcholine (MeCh) for specific ChE and Benzoylcholine (BzCh) for non-specific ChE as substrate.
Following results were obtained :
1. ChE activities of human placenta were the lowest in the mid stage, while higher in the early stage, and the highest in the last stage of pregnancy bolood.
2. Blood ChE activities of artery and vein in umbrical cord were almost the same, while remarkably higher activities were observed in maternal blood.
3. ChE activities of human placenta were the highest in the last stage of pregnancy, and then decreased gradually with the beginning and progress of the labor.
4. ChE activities of human placenta were lower in cases of early abortion, toxemia of pregnancy, and uterine intertia, and were high in cases of cesarean section without toxemia of pregnancy, and atony of uterus.
