Abstract
1. In the present study, biological observation and pathohistological survey of the kidney were made on the mice inoculated introcerebrally with ectromeria virus in varying dilutions of 10-1 to 10-10
2. Survival days of the groups received the inoculation of highly concentrated virus was short and this survival period became longer following the increase in virus dilution with wider deviation of individual survival days. Namely, the survival period became longer from the group received concentrated virus to the groups of lower concentrations.
3. It is considered that the viremia caused by the inoculation of ectromeria virus invited the development of destrutive changes on the glomeruli, especially, on the epithelium of the renal tubuli on one hand and the enhancement of vascular permeability due to the circulatory disturbance on the other resulting in the appearance of fibrous reproduction as reactional and reparative processes against such chages.
4. As for renal lesions, both tissue destructive and circulation disturbing changes existing together there was no basic difference between the glomeruli and the tubuli indicating their progress into indurated lesions.
