昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
産婦人科領域に於けるSulfisomezole (Sinomin) の治験
外山 順一林 正村上 淑郎竹之内 春男近藤 誠一
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1960 年 20 巻 5 号 p. 419-422

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Sinomin, a sulfa drug of durable effect, was administered on various infections of gynecology. Out patients of cystitis, inflammation of the genital organs and mastitis received Sinomin of the initial dose 2.0 g followed by 1.0 g every 12 hours thereafter. Evaluation of the therapeutic effect was done by the finidings of bacteriological tests and the changes observed in the subjective and objective symptoms of the patients.
The drug showed an excellent effect in the treatment of cystitis as well as the inflammation of related organs. It was effective for the treatment of the mastitis on early stage. As for the inflammations of genital organs, those which had been caused by coli bacilli and those with acute symptoms required the combined use of Penigin C suppository. Otherwise, it was not effective.
Administration of Sinomin with long intervals could show therapeutic effects comparable to the administration of other sulfa drugs with shorter intervals. Besides, the period of treatment was shortened by the use of Sinomin.
As for side reactions, urticaria was observed on one of the patients received Sinomin.
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