Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
TWO CASES OF VON RECKLINGHAUSEN'S DISEASE
Kamon TsurutaTadashi ItokawaRyoei KuwatsuruSennosuke IkedaKenzo Kato
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1960 Volume 20 Issue 7 Pages 746-751

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Abstract
Two cases of von Recklinghausen's disease were described. In the first case, there were the spots of increased skin pigmentation combined with multiple neurofibromas The pigmented spots were irregular in shape, vary in size and were of brownish in color. Neurofibromas were found generally on the body surface, especially, over the trunk. Majority of them were smoothlyrounded soft and from a few millimeters to 5 centimeters in diameter. Thinning of periosteum and fibrous dysplasia were found to have associated with this tumour. And, mental retardation was, found to run in the family of this patient. It was recognized histologically that fhe tumour arose from the neurilemmal sheath and fibroblasts of the peripheral nerve.
Findings of the second case were mostly the same as those of the first case.
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