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Volume 20, Issue 7
Displaying 1-16 of 16 articles from this issue
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Susumu Nakazawa, Yohiichi Ogawa, Hiroshi Tsujitake, Wun Yuan Lee1960 Volume 20 Issue 7 Pages 741-745
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESS -
Kamon Tsuruta, Tadashi Itokawa, Ryoei Kuwatsuru, Sennosuke Ikeda, Kenz ...1960 Volume 20 Issue 7 Pages 746-751
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTwo cases of von Recklinghausen's disease were described. In the first case, there were the spots of increased skin pigmentation combined with multiple neurofibromas The pigmented spots were irregular in shape, vary in size and were of brownish in color. Neurofibromas were found generally on the body surface, especially, over the trunk. Majority of them were smoothlyrounded soft and from a few millimeters to 5 centimeters in diameter. Thinning of periosteum and fibrous dysplasia were found to have associated with this tumour. And, mental retardation was, found to run in the family of this patient. It was recognized histologically that fhe tumour arose from the neurilemmal sheath and fibroblasts of the peripheral nerve.
Findings of the second case were mostly the same as those of the first case.View full abstractDownload PDF (3878K) -
Hiroshi Maruyama1960 Volume 20 Issue 7 Pages 752-766
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESS1. Diencephalon is known to possess the sexual center of high level. It is indispensable, therefore, to attempt fundamental central treatment of the diencephalon for the improvement of the sexual functions aside from the administration of Gonadotropin or Androgen.
As the treatment of male sterility, the author attempted the irradiation of X-ray on the diencephalon as well as the treatment by so-called rebound phenomenon due to the administration of an excessively large amount of Androgen. Besides, in an attempt to know the mode of action assays were made on varying kinds of hormons.
2. A single time irradiation of X-ray 200 roentgen on the diencephalon of normal males was found to cause a considerable variation in the number of circulating eosinophiles and in the content of blood sugar demonstrating that X-ray irradiation has a fairly strong influence on the diencephalon.
Moreover, out of the 21 cases of male sterility received X-ray irradiation of 100 roentgen twice per week for 3 weeks, increase in the sperm count was recognized on 13 cases. Excretion of 17-KS and fructose in the urine was found to have increased after irradiation, but that of Gonadotropin in the urine showed no appreciable difference.
3. On determination of Gonadotropin and 17-KS, the development of rebound phenomenon was observed on a castraied male patient administered of Testosterone heptanoate in a weekly dose of 200 mg successively for 8 weeks. Likewise, the occurrence of rebound phenomenon was observed on 2 cases of male sterility administered of Testosterone heptanoate in a dose of 250 mg twice per month for 2 months. In the patient of spermia, the appearance of sperm was negative, but there was a marked increase in the number of sperm in the patient of oligospermia.
Occurrence of rebound phenomenon was also confirmed on 2 normal males and 3 cases of oligospermia administered of an excessive amount of Testosterone preparation over a prolonged period of time.View full abstractDownload PDF (4130K) -
Tokuhiro Kanai1960 Volume 20 Issue 7 Pages 767-782
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSEpidemiological survery was made on Sueyoshi area in Hachijo Island. A total of 134 patients have already been reported in this area since 1950. On investigating the geographical distribution of the patients, the occurrence of this infection was found to be closely related with the sun shine hours. In Sueyoshi area, both the appearance and disappearance of the epidemic of Shichito fever were quicker than the other parts of the Island. In addition, the presence of recurrence and fatal cases was confirmed though both of them had been believed to be absent in the past.View full abstractDownload PDF (5787K) -
Shigeru Ouchi1960 Volume 20 Issue 7 Pages 783-804
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe author examined the influences of the intravenous injection of auto-blood diluted with an equal volume of physiological saline solution containing one percent neutral sodium citrate and almost fully raturated with CO2 upon the physiological functions and the clinical symptoms of psychic patients. The results are summarized as follows :
1. The CO2 volume of venous blood usually increased with a few exceptions, while that of arterial blood increased in almost all cases more markedly.
2. The total number of leucocytes increases, though acidphile cells decrease markedly. Erythrocytes decrease temporarily after each injection, but are increased by repeated injections.
3. The pulse rate remains unchanged. The respiration becomes deep and less frequent and irregular. These changes are peculiar to each individual. Blood pressures were elevated in two thirds of the cases examined and lowered in the rest. This lowering is observed rather often and markedly in cases of hypertension.
4. On comparison with the results obtained in the control studies using shaked auto-blood and sodium bicarbonate solution, the findings mentioned above seem to be characteristic to thee injection of auto-blood saturated with CO2.
5. As these changes are quite similar to those induced by various kinds of shock-therapies, the author applied this intravenous injection of auto-blood saturated with CO2 to psychic patients. expecting some therapeutic effects upon them. Thus, the following results were obtained :
6. The curative effects upon manics and depressives, especially upon the latter, were striking. It showed also good effects upon schizophrenics, among whom stuporous catatonics were influenced most favourably. On the other hand, a few cases of catatonia were aggravated and sometimes. excitation was brought about. The effect upon epileptics was doubtful, neurotics hardly underwent any favourable changes.
7. From these facts the author assumed that the essence of this therapeutic method consistedd rather in an activating process than in a tranquillizing one. In conclusion, he wishes to urge the significance of this new method which accompanies no side effect at all.View full abstractDownload PDF (3294K) -
Masaaki Hayashi1960 Volume 20 Issue 7 Pages 805-816
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSPathological and histochemical observations were made on the liver and the intestine of rabbits infected with Schistosoma japonicum and the course of the disintegration of infected parasite eggs in host tissues was traced.
PAS reaction, alkaline phosphatase and fatty yolk were observed in the cortex of the eggs undergone cleavage. Then, fatty yolk decreased remarkably in the matured eggs, while PAS reaction and alkaline phosphatase remained as before in this stage. Estimation of the disintegration of eggs is possible by the cytoplasmic structure, nerve or eosinophilic glands, or histochemically by the lipoid content and distribution in the eggs.
It is concluded that the integration of eggs is conducted not by the grade of maturity but by their enviromental eonditions in the host tissues.View full abstractDownload PDF (8980K) -
Shigemichi Nakamura1960 Volume 20 Issue 7 Pages 817-826
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSVarious combinations of tube voltage and grid ratio were examined to, satisfy the following conditions in high voltage techinique of the chest.
Comparable or better findings concerning the fine petails of soft tissues, calcification and minor blood vessels underlying ribs in comparison with 60 kVp without rid were obtained in the voltage ranging from 80 to 140 kVp. Quantitative determinations of patient's exposure were carried out, which was one of the important factors in the improvement of chest radiography.
Results were as follows :
1. To secure the findings of fine details of soft tissue, it is only necessary to combine the grid of low ratio with high voltage.
2. Combination of high voltage and high grid ratio is preferable for the observation of the fine details of blood vessels underlying ribs.
3. For calcification, low voltage and low grid ratio is desirable.
4. Combination of high voltage and low grid ratio can improve radiogram and reduce patient's exposure time.
5. In general, various combinations of voltage and grid ratio can be adopted as standard in routine work : 80 kVp and 4: 1, 100 kVp and 6: 1, 120 kVp and 8: 1, 140 kVp and 12: 1, 140 kVp and 5: 1 cross grid.View full abstractDownload PDF (3620K) -
1. Budding of Pollen GrainHiroshi Sakakibara, Haruo Kubota, Shigemichi Nakamura, Minoru Sonoe1960 Volume 20 Issue 7 Pages 827-828
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSPollen grain fails to bud when irradiated prior to meiosis. On this account, it is considered that the meiosis is the epoch to radiation injury. In our experiment, it was decided that the sensitivity became lower when the time of irradiation was more distant and elevated again in mitosis. The time prior to meiosis is not the critical time. The sensitivity of pollen grain is high not noly in meiosis but also in nucleus division as other cells.View full abstractDownload PDF (189K) -
Kenichi Okamoto, Tokuhiro Kanai, Kazuo Mori1960 Volume 20 Issue 7 Pages 829-832
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe present study was undertaken to determine whether the presence of a cancerous growth affects in certain changes on epidermal mitotic activity of the host animal.
A decrease in the epidermal mitotic activity and the relationship between tumour growth and epidermal mitotic activity was observed in mice bearing transplanted Ehrlich ascites tumour.
Decrease in the epidermal mitotic activity was more significant when the tumour was ascitic than was solid. A significant decrease in the epidermal mitotic activity was also observed in the ears of mice when they received toxohormone injection at 24 hours.View full abstractDownload PDF (441K) -
Tsuneo Murakami1960 Volume 20 Issue 7 Pages 833-850
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSAn attempt was made to learn the toxicity of quinidine from its influence on the hatching of the fertilized hens' eggs, and further, the influence on the development of the chick embryo was observed. Furthermore, the influence and distribution of quinidine on the egg yolk, allantoic fluid, amniotic fluid and various organs, and the degradation of quinidine in homogenated liver and kidney of chick embryo and chicken was investigated. The principal results thus obtained are as follows.
1) In the case received the injection of 8 mg of quinidine, perfect hatching of the chick embryo was hardly obtained.
2) When quinidine was applied, the development of the chick embryo was inhibited.
3) The concentration of quinidine in the egg white and egg yolk was found to decrease as the incubation progressed.
4) The excretion of quinidine into the allantoic fluid increased gradually to reach the maximum on the 18th day of the incubation.
5) The content of quinidine in the amniotic fluid attained to the highest rate on the 18 th day of the incubation.
6) Quinidine was distributed in the largest amount in the liver followed by the brain, heart and kidney.
7) The rate of decomposed quinidine on the homogenated liver reached the maximum in the case on the 16th day of incubation, and thereafter were found decreased as the incubation progresed.
8) The rate of decomposed quinidine on the homogenated kidney increased gradually to reach the maximum on the case of chicken.View full abstractDownload PDF (2387K) -
Fumio Yoshida1960 Volume 20 Issue 7 Pages 851-859
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSLD50 of ectromelia virus Dobashi strain was found to be 10-6.2 by intracerebral cnoculation made on mice. Then, the mice inoculated intracerebrally with 100% lethal dose of the virus was sacrificed on every other day following the inoculation for the comparison of the histological changes produced in the brain. Then, each virus of different disease days was subjected to the quantitative determination for the calculation of the motality rate, lethal power and LD50 in order to know the biological changes produced in the nature of the intracerebral virus.
Small vacuoles formed along the vascular wall of capillaries are considered to be the primary manifestation of the rupture of blood-brain barrier indicating the tissue disturbance of central nerves and the starting point of visceral stage. On the other hand, retardation of the proliferation of intracerebral virus by the inhibition of blood-brain barrier was known from the growth curve of the virus.
Marked proliferation of the fibrous macrogyria observed on Ammon horn is considered to have the primary significance in relation to the appearance of spasms like in the case of epilepsy rather than the secondary reparative changes.View full abstractDownload PDF (5592K) -
Shoichi Hara1960 Volume 20 Issue 7 Pages 860-871
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn the present study, a mammary tumour spontaneously developed in a mouse of dbr strain was transplanted on the male mice of the same strain and Enarmon and Parotin injections were made before and after transplantation of the tumour under varying conditions for the histopathological observation of their influence on the development of the tumour itself as well as on the surrounding tissues, especially, on the skin covering it with special reference on the hydropic lesions.
1. Atrophy and thinning of the epidermis of the skin covering tumour were found to parallel the size of tumour when it was spherical.
2. Histopathological changes due to the transplantation of tumour observed on the mice of Enarmon administration were comparable to those of the control group being much severer than those observed on the mice of Parotin administration with more marked tubular and cystomatoid formation. These findings are in agreement with the theory to say that, in the study of mammary tumour, the organs which have undergone higher histological differentiation show quicker growth rate.
3. Throughout these two experimental groups, all cases showed the presence of marked hydropsia in the subcutaneous tissue and the infiltrative proliferation of tumour cells into it with only 1 exception necessitating the important role played by hydropsia in the expansion of the tumourous tissue.View full abstractDownload PDF (4954K) -
Toru Doi1960 Volume 20 Issue 7 Pages 872-886
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSVarying dilutions of ectromelia virus were inoculated into the chorioallantoic cavity (first experiment) and amnionic cavity of the embryonating eggs. By successive passage in the former and by the difference in the dilution of virus inoculated in the latter, biological observations were made on the development of eggs as well as on the mice inoculated with varying test materials. At the same time, moreover, histopathological investigations were made on the changes of various egg membranes (allantoic membrane, amnionic membrane and inner shell membrane) produced at the site of inoculation and those of the different locality as well as the changes by the difference in the concentration of virus inoculated.
In both the first and the second experiments, macroscopic changes were severer, mortality rate was higher and the survival period was shorter in the earlier stage of transplantation and with higher concentration of the inoculum used. As for the histological findings of the shell membrane, the eggs on earlier stage of transplantation and those received the inoculum of higher concentration showed stronger degenerative changes with only moderate hydropic changes. While, the eggs on the later stage of transplantion and those received the inoculum of lower concentrationn showed much weaker degenerative changes with advanced hydropic changes in both experiments.
It isconsidered that both the difference in the amount of virus inoculated and the number of transplantations repeated are influencing each other on the multiplication of virus as well as the destruction of the metabolic processes of normal cells by the toxic effect of the virus and the disturbance of blood circulation producing the changes stated above.View full abstractDownload PDF (6229K) -
Akihiko MUSASHI1960 Volume 20 Issue 7 Pages 887-888
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (244K) -
Akihiko Musashi1960 Volume 20 Issue 7 Pages 889-891
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (278K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1960 Volume 20 Issue 7 Pages 892-893
Published: October 30, 1960
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (264K)
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