Abstract
It has long been known that when one side renal function is impaired or one side nephrectomy is applied by some cause or the other, the remaining kidney shows compensatory hypertrophy. With an intention of knowing the main cause of this hypertrophy, one side nephrectomy was applied on Wister rats and the remaining kidney was subjected to the histological investigation following the lapse of time.
1. No increase was recognized in the number of gromeruli.
2. Histological change were characterized by the hyperplasia and hypertrophy of Bowman's capsule, grommeruli and tubules. The rate of increase in size was rapid for about 40 days after nephrectomy and gradually slowed down thereafter. No significant changes were observed on the interstitial tissue.
3. Following the advance in compensatory renal hypertrophy, the kidney gradually became spheric in shape which might due to the hypertrophy of nephron.
