Abstract
The postoperative adhesion of the intestine is still the greatest trouble in the abdominal surgery.
Recently, Dr. Wakisaka reported that the intraabdominal infusion of 1% Chondron liquid is efficient for the prevention of the intestinal adhesion and Dr. Yamanaka reported also the good effect of that of 7% P. V. P, for the some purpose.
The author tried the same liquids in the animal experiment, but could not find the excellent effects as these investigaters had reported.
Concequently the author tried other liquids as Silicone or changed the liquid concentration of Chondron or P. V. P. or at last used the mixed solution of Chondron and P. V. P. of different concentration.
As the result one of the last methods (The infusion of the mixture of 1% Chondron and 7% P. V. P.) showed the most excellent effects in both animal experiments and clinical investigation. In the animal experiments the author used 47 of dogs and 39 of rabbits and examined the Specimens pathohistologically. In the clinical investigation he observed the clinical processes of 62 patients who were infused with the mixture by the relaparotomy according to the intestinal adhesion for 4 years from 1958 to 1962.
Only 3 (4.8%) out of these 62 patients needed the third laparotomy, against the 11.1% of control group by whom the preventative method was not used by the relaparotomy with the same reason.
So the author concluded the report in recommending the infusion of the mixture of 1% Chondron and 7% P. V. P. into the abdominal cavity at every laparotomy for the prevention of the intestinal adhesion.
