Abstract
The action of NH4Cl on the cerebral circulation and the effects of sodium, magnesium or potassium aspartate on the ammonia action in the cerebral circulation were studied and the following results were obtained.
1) When NH4Cl was injected into vein, the blood pressure (BP) was decreased temporarily while no effects were observed in the cerebral blood flow (CBF) and the cerebral vaso-resistance (CVR) .
2) When NH4Cl was injected into artery, BP was decreased temporarily and CBF was increased while CVR was decreased.
3) The decrease of CVR caused by the intravenous injection of NH4Cl was inhibited by the premedication of sodium, magnesium or potassium aspartate.
4) The increase of NH3level in blood caused by the intravenous injection of NH4Cl was inhibited by the premedication of sodium, magnesium or potassium aspartate.
