抄録
A case of aplastic anemia with relative hyperplasia of normoblast in the bone marrow, which has been considered to be very rare in the childhood was reported.
This nine year eleven months old boy was admitted to the Showa University Hospital on the July 1 st., 1967 because of epistaxis. He has had history of bruising and buccal bleeding since his six years of age, on and off. Three days prior to the admission, he has had epistaxis suddenly in the morning followed by daily episode. On the June 30, the episode of nasal bleeding strengthened and lasted few hours.
On his past history, chloramphenicol had been given in the occasion of acute upper respiratory infection by his family physician intermittently. Otherwise, no contributable history was taken.
Physical examination on the admission revealed moderatory pale colored skin and epstaxis without any other positive finding. On laboratory studies, he had hypocellular bone marrow with hyperplasia of normoblastic series. The elevated serum iron and normochromic, normocytic anemia with decreased number of white cells and platelet count enabled us to establish the diagnosis of aplastic anemia beside bone marrow finding.
Prednisone was initiated daily followed each tow day administration and partial remission was obtained few months later. Since then, few episodes of similar course had been repeated till complete remission obtained under intermittent administration of steroid hormone.
Patient is still under observation by our out-patient-clinic and doing well for two years six months after establishing the diagnosis.
