大腿四頭筋拘縮症に関する研究

第1編臨床的研究第2編実験的研究 (注射が筋に及ぼす影響について)

抄録

The objects of this paper are to suggest an important factor in the etiology of contracture of the quadriceps muscle is the giving of intramuscular injections and transfusions of Ringer fluid into the thighs. After clinical and experimental study, the results are descrived as follows:
1 All the clinical cases of the quadriceps muscle contracture had received injections or transfusions into the thighs.
2 Sixty percents of the clinical cases had received injections of antibiotics or transfusions.
3 All the operated cases had more or less the fibrous degenerations in the rectus femoris muscle.
4 After five or ten years, the further restriction of flexion tends to be caused by the operation of incision and lengthening of the rectus femoris muscle at its origin.
5 A reoperation is necessary, because the bone does not grow up in parallel with the affected muscle fiber.
6 In the group of subcutaneous transfusions of Ringer fluid, fibrous degeneration of the muscle fiber was observed at the subcutaneous layers or the muscle layers under the transfused regions.
7 In the group of intramuscular transfusions of Ringer fluid, the effect to the muscle fiber is slight than the group of subcutaneous transfusions.
8 In the group of subcutaneous injections, the pathological findings is same as the subcutaneous transfusions.
9 In the group of muscle injections of chloramphenical, fibrosis, atrophy and regressive degeneration in the muscle fibers are observed relative localizedly or at times diffused. This finding occurs with repeated injections and parallels injected dosage and the number of times.
10 It is considered that fibrosis and atrophy of the muscle fiber in the experiment combine not directly with the quadriceps contracture. To think about the experimental results, muscle degeneration suggests an important factor in the etiology of the quadriceps muscle contracture.