剖検例による腎糸球体の量的解析

―平均糸球体数と平均糸球体面積について―

抄録

In 89 autoptic kidneys, the average number in a given zone (1 mm²) and the average area of glomeruli were determined by means of manual optical picture analyzer (abb. MOP) . Their variations with age were discussed and also their relations with the renal weight were studied.
The results were as follows ;
1) The weight of the kidney tended to increase from the first day of birth, reach at the level almost equal to the adult one in the late teens, and reduce rather gradually after the 70's.
2) The average number of glomeruli present in a given zone (1 mm²) was about 30 on the first day of birth ; then, it reduced to about 5, which is equal to the adult one, in the late teens, but tended to reduce gradually after the 40's.
3) The average area of glomeruli was about 4, 000μ²on the first day of birth, then was increasing to about 20, 000μ²in the early teens to be almost equal one. In the adults after the 20's, the average area of glomeruli did not change.
4) The relations between the renal weight and the average number of glomeruli in a given zone (1 mm²) and between the renal weight and the average area of glomeruli were studied on adults' kidneys, but no correlative relation was observed.