Abstract
Serum level of monoamine oxidase (MAO) was determined in 92 patients with digestive diseases (gastric and duodenal ulcers, gastric cancer, colon cancer and hepato-bileduct disorder) . Significant change in serum MAO level was not observed in patients with these digestive diseases. Marked elevated serum MAO level was found in patients with early gastric cancer, while no change was observed in patients with scirrhous gastric cancer. No difference in serum MAO level was observed between in patients with advanced gastric cancer and with early gastric cancer. Marked elevated MAO level was observed in patients with scar stage of gastric and duodenal ulcers, while not found in patients with ulcer stage of them. No marked change in serum MAO level was observed between in patients with scar stage of gastric and duodenal ulcers and with ulcer stage of them. Serum MAO levels in patients with advanced cancer, early gastric cancer, gastric and duodenal ulcers, gallbladder disorder and colon cancer were determined from the period of preoperation to 14 days after operation and found no marked change in serum MAO level throughout these periods. Regression analysis demonstrated that serum MAO level was not correlated to serum GOT level, value of thymol turbidity test and number of platelet. From these results, it is suggesting that measurement of serum MAO level is not useful tools for the diagnosis of these digestive diseases.
