Abstract
In order to find out Mg metabolism for the perinatal period, Mg and its hormonal control factor (aldosterone, iPTH etc.) and Ca, P was measured in samples of plasma for 77 normal mature neonates and 84 immature neonates without sickness and 17 maternal, 26 umbilical venous blood, 21 umbilical arterial blood and 105 sick neonates (RDS, hypocalcemia, hypomagnesemia etc.) and 94 normal children. The following results were obtained. 1. It was found that both Mg and aldosterone crossed the placenta. 2. These data suggest that in both the fetus and the neonates after the age of 48 hrs, aldosterone may partly influence the Mg levels. 3. There was lower the mean plasma Mg levels and higher the mean plasma aldosterone levels in sickneonates (particulary in RDS) than normal neonates. These data indicated that we should take a count of hyperaldosteronism was a cause of hypomagnesemia in sick neonates.
