Abstract
Since it became known in the year 1889, the etiology of this syndrome has been studied on various aspects. Many investigators have demonstrated the genetic aspect of this disease. In fact, the autosomal dominant inheritance factor is now quite clear. Genetic transmission of this syndrome has been reported in 60 cases nationwide. In the present study, the disease was passed from father to son. We have reviewed the literature, especially that on family histories of Japanese suffering from Treacher Collins Syndrome, as hereditary transmission was establiahed in this study.
