THE DIFFERENCE OF T-CELL POPULATION BETWEEN HODGKIN'S DISEASE OF MIXED CELLULARITY TYPE AND SPECIFIC GRANULOMATOUS LIMPHADENITIS WITH HIGH CONTENT EPITHELIOID CELLS

—INVESTIGATION BY ALPHA-NAPHTHYL-ACETATE-ESTERASE STAIN—

Abstract

We reported here the difference of T cell Population between 19 cases of Hodgkin's disease of Mixed Cellularity (the first group) and 24 cases of various specific granulomatous lymphadenitis including tuberculosis, toxoplasmosis, sarcoidosis and lues (the second group) by using ANAE stain. The both groups are commonly formed small and/or large clustered epithelioid lesions histologically. ANAE-Droplet positive cell (T cell) is more prominent in the lymphadenitis than that of Hodgkin's disease. It may be indicated that the co-operation of T cell and histiocyte-epithelioid cell is preserved in process of diseases to do antigen clearance. On the contrary, in the neoplastic process, such this report as the lesion of Hodgkin's disease, it may be suggested to happen not only the functional T cell defect but the disturbance of co-operation between histiocyte-epithelioid cell and T cell.