A CASE OF THE OLD WOMAN WITH DIABETES INSIPIDUS ASSOCIATED WITH REFRACTORY CORNEAL ULCER AND SYPHILIS

Abstract

A 75-year-old woman with refractory corneal ulcer, iritis, scleromalacia and polyclonal gammopathy was admitted to examine the relationship between systemic diseases and those ophthalmological symptoms. After admission, polyuria and polydipsia developed. Although the primary diabetes insipidus was strongly suggested by the positive results of water deprivation test, Carter-Robbins test and DDAVP test without pathological findings on skull X-ray film and brain CT scan, the definite diagnosis could not be made due to various clinical manifestations, such as polyclonal gammopathy, trigeminal neuralgia, diabetes mellitus and positive serum reaction with TPHA. The problems whether these clinical symptoms were related to the cause of diabetes insipidus or they were observed as complications of the disease would be clarified by intensive follow up study.