Abstract
Short-term prognosis of acute myocardial infarction (AMI) and classification of congestive heart failure (CHF) by hemodynamic variables were assessed by multivariate analysis using a disciminant function. One hundred and forty patients with AMI (122 hospital survivors and 18 non-survivors) were studied. Hemodynamic variables were measured on admission (0 hour), and 8, 16 and 24 hours after admission. Standardized scores of BPS, BPM, BPD, HR, CI, PCWP and CVP were calculated. The discriminant effect was proved to be greater in the order of CI, CVP, PCWP and BPD. The following two discriminant equations were obtained.
Z=223-164 (CI) +10 (PCWP) (I)
Z=-42-27 (BPS) -64 (BPD) +88 (BPM) +3 (HR) -136 (CI) +7 (PCWP) +13 (CVP) (II)
When variables at 0 hour were used, the above equations were proved to be best to discriminate between hospital survivors and non-survivors. That is, the rates of correct discrimination were 78.8 % after the equation I and 85.6 % after the equation II when the internal sample was used, and 76.2 % after the equation I and 85.7 % after the equation II when the external sample was used. CI of 2.36 l/min/m2and PCWP of 15 mmHg could satisfactorily classify the severity of CHF into 4 stages.
